CAS No. : 1522418-41-2
(Synonyms: LY3314814 (camsylate); AZD3293 (camsylate))
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| Cat. No. : | HY-100740B |
| M.Wt: | 644.82 |
| Formula: | C36H44N4O5S |
| Purity: | >98 % |
| Solubility: |
Lanabecestat (AZD3293; LY3314814) camsylate is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. Lanabecestat camsylate is used for the research of Alzheimer's disease[1]. In Vivo:lanabecestat (5-25 mg/kg; p.o) camsylate displays significant dose- and time-dependent reductions in plasma, cerebrospinal fluid, and brain concentrations of Aβ40, Aβ42, and sAβPPβ in mice, guinea pigs, and dogs[1].
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