Sulfalene


CAS No. : 152-47-6

(Synonyms: Sulfametopyrazine; AS-18908)

152-47-6
Price and Availability of CAS No. : 152-47-6
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50mg $30 In-stock
100mg $50 In-stock
500mg $125 In-stock
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Cat. No. : HY-A0130
M.Wt: 280.30
Formula: C11H12N4O3S
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic;warming)
Introduction of 152-47-6 :

Sulfalene (Sulfametopyrazine) is an orally active antimalarial agent. Sulfalene competes with para-aminobenzoic acid in plasmodial and bacterial folic acid synthesis pathways. Sulfalene reduces trachoma-associated pathological changes. Sulfalene can be used for the research of acute falciparum malaria, Schistosoma mansoni infection, trachoma, chronic bronchitis, and bacteriuria in pregnancy[1][2][3][4][5]. In Vitro:Sulfalene exhibits antitrachoma activity in yolk sacs of embryonated chicken eggs[3].
Sulfalene has a free, active fraction of 35%-45% in human plasma, representing a higher biologically available portion than Fanasil[3].

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