Avitriptan


CAS No. : 151140-96-4

(Synonyms: BMS 180048)

151140-96-4
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Cat. No. : HY-105082
M.Wt: 458.58
Formula: C22H30N6O3S
Purity: >98 %
Solubility:
Introduction of 151140-96-4 :

Avitriptan is a 5-HT1B/1D receptor agonist, with pKis of 7.44 ( 5-HT1B rat), 7.68 ( 5-HT1B human) and 8.36 ( 5-HT1D human). Avitriptan constricts the isolated coronary artery. Avitriptan can be used for migraines[1]. IC50 & Target:pKis: 7.44 ( 5-HT1B rat), 7.68 ( 5-HT1B human), 8.36 ( 5-HT1D human), 7.15 ( 5-HT1A rat), 5.68 ( 5-HT2 rat) and <6 (5-HT3 rat)

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