Pramlintide
CAS No. : 151126-32-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $180 | In-stock |
| 10mg | $280 | In-stock |
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| Cat. No. : | HY-P0058 |
| M.Wt: | 3949.39 |
| Formula: | C171H267N51O53S2 |
| Purity: | >98 % |
| Solubility: | H2O |
Pramlintide is a polypeptide analogue of human amylin. Pramlintide, an antidiabetic agent, is antineoplastic in colorectal cancer[1].
In Vitro: Pramlintide inhibits the growth of HCT-116 and HT-29 in a dose-dependent manner, with higher efficacy against the latter (IC50s of 48.67 and 9.10 μg/mL, respectively)[1].
The addition of 5, 10, and 20 μg/mL of Pramlintide to HCT-116 and HT-29 with 5-fluorouracil, Oxaliplatin, or Irinotecan induces the antiproliferative effect synergistically[1].
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