Balofloxacin (dihydrate)
CAS No. : 151060-21-8
(Synonyms: Q-35 (dihydrate))
| Size | Price | Stock |
|---|---|---|
| 250mg | $35 | In-stock |
| 500mg | $56 | In-stock |
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| Cat. No. : | HY-B0159A |
| M.Wt: | 425.45 |
| Formula: | C20H28FN3O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections[1][2].
In Vitro: Balofloxacin (25 mg/mL; 1 h) decreases the growth of S. aureus that adhered to human corneal epithelial cells (HCECs)[2].
Balofloxacin inhibits the S. aureus ATCC 25923, with a MIC of 0.125 mg/mL[2].
Balofloxacin (0.05-500 μg/mL; 72 h) does not induce toxicity on the HCECs at a low concentration, such as 0.625 mg/mL[2].
In Vivo: Balofloxacin (200 mg/kg/day; p.o. for 5 d) reduces the counts of viable M. pneumonia in the lungs of hamsters[3].
Balofloxacin eye drops (0.5%) is effective in S. aureus bacterial keratitis of rabbits[2].
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