WIN 64338
CAS No. : 151039-63-3
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| Cat. No. : | HY-101368 |
| M.Wt: | 747.47 |
| Formula: | C45H68ClN4OP |
| Purity: | >98 % |
| Solubility: |
WIN 64338 is a non-peptide bradykinin B2 receptor antagonist. WIN 64338 can inhibit bradykinin-evoked trigeminal nerve stimulation[1].
In Vitro:WIN 64338 (1-10 μM, 30 mins) competitively antagonizes bradykinin-evoked contractile responses in isolated rabbit iris sphincter with a pKB of 6.6[1].
In Vivo:WIN 64338 (30-300 nmol/kg, i.v., 15 min before bradykinin administration) inhibits bradykinin-induced conjunctival and nasal mucosa plasma extravasation in guinea pigs[1].
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