MC-DOXHZN
CAS No. : 151038-96-9
(Synonyms: (E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone)
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| Cat. No. : | HY-16261A |
| M.Wt: | 750.75 |
| Formula: | C37H42N4O13 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
MC-DOXHZN ((E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone) is an albumin-binding proagent of Doxorubicin (HY-15142A) (DNA topoisomerase II inhibitor), with acid-sensitive properties. MC-DOXHZN can be used to synthesize ADC[1]. In Vitro:MC-DOXHZN conjugates to DTT-thiolated monoclonal antibodies (chimeric BR96, BR64, L6, human IgG) to form stable thioether-linked immunoconjugates[1].
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