Cholesteryl hemisuccinate
CAS No. : 1510-21-0
| Size | Price | Stock |
|---|---|---|
| 5g | $26 | In-stock |
| 25g | $129 | In-stock |
| 100g | $500 | In-stock |
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| Cat. No. : | HY-W010800 |
| M.Wt: | 486.73 |
| Formula: | C31H50O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 60°C);Ethanol : 25 mg/mL (ultrasonic) |
Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth[1][2]. In Vivo:Cholesteryl hemisuccinate (100 mg/kg; ip; single dose before AAP) abrogates histological and biochemical diagnostics of both apoptosis and necrosis induced by AAP (350-500 mg/kg; ip; single dose) in ICR mice (CD-1)[1].
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