Perospirone
CAS No. : 150915-41-6
(Synonyms: SM-9018 (free base))
| Size | Price | Stock |
|---|---|---|
| 5mg | $77 | In-stock |
| 10mg | $132 | In-stock |
| 25mg | $288 | In-stock |
| 50mg | $462 | In-stock |
| 100mg | $792 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-B0731A |
| M.Wt: | 426.57 |
| Formula: | C23H30N4O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 5 mg/mL (ultrasonic) |
Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT2A receptor (Ki=0.6 nM) and dopamine D2 receptor (Ki=1.4 nM), and also a partial agonist of 5-HT1A receptor (Ki=2.9 nM). Perospirone is an atypical antipsychotic agent and has the potential for schizophrenic disease research[1][2]. In Vitro: Perospirone (SM-9018 free base) possesses moderate affinities for α1, 5-HT1, and D1 receptors (Ki=17, 18 and 41 nM, respectively) [1]. In Vivo: Perospirone (SM-9018 free base; 1.0-10.0 mg/kg/day; orally; for 14 consecutive days) significantly attenuates PCP-induced cognitive deficits in mice in a dose-dependent manner[2].
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