Procyclidine (hydrochloride)
CAS No. : 1508-76-5
(Synonyms: Tricyclamol (hydrochloride); (±)-Procyclidine (hydrochloride))
| Size | Price | Stock |
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| Cat. No. : | HY-B1487 |
| M.Wt: | 323.90 |
| Formula: | C19H30ClNO |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C);H2O : 5.56 mg/mL (ultrasonic;warming;heat to 60°C) |
Procyclidine (Tricyclamol, (±)-Procyclidine) hydrochloride , an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine hydrochloride can be used in studies of Parkinson's disease and related psychiatric disorders such as Soman-induced epilepsy[1][2].
IC50 & Target: NMDA Receptor[1]
In Vivo: Procyclidine (subcutaneous injection, 0.3-6.0 mg/kg) hydrochloride in combination with physostigmine (PhS) increases protection in a dose-dependent manner in rats and guinea pigs infected with soman and can prevent seizures altogether[1].
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