Tropicamide


CAS No. : 1508-75-4

(Synonyms: Ro 1-7683)

1508-75-4
Price and Availability of CAS No. : 1508-75-4
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500mg $80 In-stock
1g $105 In-stock
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Cat. No. : HY-B0321
M.Wt: 284.35
Formula: C17H20N2O2
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic)
Introduction of 1508-75-4 :

Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. When used as an eye drop, Tropicamide causes short-term mydriasis (pupil dilation) and cycloplegia. Tropicamide can be used in the research of neurological diseases, such as epilepsy[1][2][3][4]. IC50 & Target:mAChR M4[1] In Vivo:Tropicamide (2, 5 mg/kg, i.p., single dose) improved perseverative behavior and learning and memory in Fmr1KO mice, and reduced the occurrence of seizures[3].
Tropicamide (1.25–20.0 mg/kg, i.p., single dose) reduces Pilocarpine (HY-B0726A)-induced tremulous jaw movements in Rats[4].

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