PD-143188
CAS No. : 150013-70-0
(Synonyms: CI 1007)
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| Cat. No. : | HY-19186 |
| M.Wt: | 329.48 |
| Formula: | C24H27N |
| Purity: | >98 % |
| Solubility: |
PD-143188 (CI 1007) is a selective agonist targeting dopamine (DA) receptors, with Ki values of 25.5 nM and 16.6 nM for human D2 and D3 receptors, respectively and lower affinity for D4.2 receptors (Ki=90.9 nM). PD-143188 inhibits DA release, synthesis and metabolism, while reducing cellular cyclic AMP levels, exerting antipsychotic activity. PD-143188 is promising for research of psychopharmacology[1].
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