GCA-186
CAS No. : 149950-61-8
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| Cat. No. : | HY-116528 |
| M.Wt: | 330.42 |
| Formula: | C19H26N2O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
GCA-186 is a potent anti-HIV-1 agent. GCA-186 is highly active against both wild type and mutated HIV-1 strains with EC50s of 1, 180, 1, and 40 nM for IIIB, IIIB-R(Y181C), NL4-3 and NL4-3K103N of HIV-1 strains, respectively[1]. In Vitro: GCA-186 shows antiviral activity (EC50=0.6 nM) and cytotoxicity against HIV-1 in MT-4 cells (CC50=43 μM)[2].
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