Emivirine
CAS No. : 149950-60-7
(Synonyms: MKC-442)
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| 10mg | $250 | In-stock |
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| Cat. No. : | HY-15353 |
| M.Wt: | 302.37 |
| Formula: | C17H22N2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine displays potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity[1][2].
In Vitro: Emivirine (EMV) is also specific for HIV-1 RT and was without effect on HIV-2[2].
Emivirine (EMV) has no obvious toxicity for human healthy cells[2].
In Vivo: Tthe approximate lethal oral dose of Emivirine (EMV) for rats was ≥3 g/kg for males and 2.5 g/kg for females[2].
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