Saquinavir (mesylate)
CAS No. : 149845-06-7
(Synonyms: Ro 31-8959/003)
| Size | Price | Stock |
|---|---|---|
| 5mg | $35 | In-stock |
| 10mg | $55 | In-stock |
| 25mg | $102 | In-stock |
| 50mg | $154 | In-stock |
| 100mg | $209 | In-stock |
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| Cat. No. : | HY-17003 |
| M.Wt: | 766.95 |
| Formula: | C39H54N6O8S |
| Purity: | >98 % |
| Solubility: | DMSO : 16.67 mg/mL (ultrasonic) |
Saquinavir (Ro 31-8959) mesylate is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir mesylate also has anti-inflammatory activity and can induce apoptosis of human red blood cells[1][2][3].
In Vitro:Saquinavir (2.5-15 μg/mL; 48 h) mesylate can induce the apoptosis of human red blood cells, and the mechanism involves the generation of ROS and the influx of Ca2+[1].
In Vivo:Saquinavir (250-2500 mg/kg; administered via diet; 1 month) mesylate exhibits anti-HIV activity in the thy/liv-SCID-hu mouse model[2].
Saquinavir (0.5 mg/kg; twice) mesylate has a protective effect in the mouse model of lung injury induced by hepatic ischemia-reperfusion (I/R)[3].
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