TNKS1/2-IN-2
CAS No. : 1498300-35-8
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| Cat. No. : | HY-153259 |
| M.Wt: | 499.48 |
| Formula: | C26H24F3N3O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
TNKS1/2-IN-2 (Compound 21) is a potent and selective tankyrases inhibitor. TNKS1/2-IN-2 exhibits IC50 values of 4 nM and 63 nM against TNK1 and TNK2 in the enzymatic assay, respectively. TNKS1/2-IN-2 inhibits proliferation of A549 and H292 cell lines with IC50 values of 39.5 nM and 12.8 nM, respectively. TNKS1/2-IN-2 can be used for the research of cancer[1].
IC50 & Target:IC50: 4 nM (TNK1); 63 nM (TNK2); 39.5 nM (A549 cell); 12.8 nM (H292 cell)[1].
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- TNKS1/2-IN-2
- Cat. No.:
- HY-153259
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