HI-346


CAS No. : 149486-68-0

149486-68-0
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Cat. No. : HY-118711
M.Wt: 340.28
Formula: C14H18BrN3S
Purity: >98 %
Solubility:
Introduction of 149486-68-0 :

HI-346 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) for HIV-1 with an IC50 value against the HIV-1 virus strain (HTLV-IIIB) of 3 nM. HI-346 is a vaginal bactericidal contraceptive agent, with its sperm-killing activity having an EC50 value of 42 μM. HI-346 shows no cytotoxicity to normal cells at effective concentrations. HI-346 can be used in anti-HIV-1 and contraceptive research[1].

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