Enalapril (sodium)
CAS No. : 149404-21-7
(Synonyms: MK-421 (sodium))
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| Cat. No. : | HY-B0331B |
| M.Wt: | 398.43 |
| Formula: | C20H27N2NaO5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Enalapril (MK-421) sodium is an angiotensin-converting enzyme (ACE) inhibitor, can be used for hypertensive diseases research[1][2]. In Vitro: Enalapril sodium (10-20 μM) has an antiarrhythmic effect in ultrafiltered PV sleeve preparation isolated from canine hearts which can inhibit EAD and DAD-induced activity[1]. Enalapril sodium (50 μM, 24 hours) inhibits the induction of apoptosis by patient serum only when used prior to treatment of HUVEC with Alzheimer's disease (AD) serum[2]. Pure Enalapril sodium has better thermal stability than pure Enalapril[3]. In Vivo: Enalapril sodium (intraperitoneal injection, 0.03 mg/kg, once) reduces infarct volume due to middle cerebral artery occlusion and lower or higher doses are ineffective in Male NMRI mice[4].
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