Sardomozide
CAS No. : 149400-88-4
(Synonyms: CGP 48664; SAM-486A)
| Size | Price | Stock |
|---|---|---|
| 5mg | $120 | In-stock |
| 10mg | $200 | In-stock |
| 25mg | $398 | In-stock |
| 50mg | $637 | In-stock |
| 100mg | $1020 | In-stock |
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| Cat. No. : | HY-13746 |
| M.Wt: | 230.27 |
| Formula: | C11H14N6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM. IC50 & Target: IC50: 5 nM (SAMDC)[1] In Vitro: Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control[1]. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells[2].
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