Thrombospondin-1 (1016-1023) (human, bovine, mouse)
CAS No. : 149234-04-8
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|---|---|---|
| 5mg | $140 | In-stock |
| 10mg | $225 | In-stock |
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| Cat. No. : | HY-P0144 |
| M.Wt: | 1128.39 |
| Formula: | C56H81N13O10S |
| Purity: | >98 % |
| Solubility: | H2O : 14.29 mg/mL (ultrasonic) |
Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide[1]. In Vitro: Thrombospondin-1 (1016-1023) (human, bovine, mouse) (4N1K; 100 µg/mL; for 60 min) treatment has induced both phosphatidylserine exposure and loss of cell membrane integrity in monocyte-derived immature dendritic cells (DCs). With peptide concentrations of 25-200 µg/mL, the number of annexin V+ cells increased with peptide concentration. Thrombospondin-1 (1016-1023) (human, bovine, mouse) reduces mitochondrial membrane potential and fragmented DNA in DCs[2].
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