6-Ethyl-7-hydroxy-4-methyl-2H-chromen-2-one
CAS No. : 1484-73-7
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| 1g | $193 | In-stock |
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| Cat. No. : | HY-W043574 |
| M.Wt: | 204.23 |
| Formula: | C12H12O3 |
| Purity: | >98 % |
| Solubility: |
6-Ethyl-7-hydroxy-4-methyl-2H-chromen-2-one (Compound 32), a derivative of Coumarin (HY-N0709), acts as a Mcl-1 inhibitor with a Ki of 5.47 μM and an IC50 of 30.88 μM. 6-Ethyl-7-hydroxy-4-methyl-2H-chromen-2-one is applicable for cancer research[1]. In Vitro:6-Ethyl-7-hydroxy-4-methyl-2H-chromen-2-one (0.01-1000 μM; 30 min) inhibits the Mcl-1-BH3 peptide interaction with a Ki of 5.47 ± 0.09 μM and an IC50 of 30.88 ± 6.12 μM in a fluorescence polarization-based binding assay[1].
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