ML-290


CAS No. : 1482500-76-4

1482500-76-4
Price and Availability of CAS No. : 1482500-76-4
Size Price Stock
5mg $135 In-stock
10mg $215 In-stock
25mg $432 In-stock
50mg $690 In-stock
100mg $1100 In-stock
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Cat. No. : HY-112606
M.Wt: 506.49
Formula: C24H21F3N2O5S
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 1482500-76-4 :

ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1]. ML290 is a biased allosteric agonist at the relaxin receptor RXFP1. IC50 & Target: EC50: 94 nM (RXFP1)[1] In Vitro: ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1].
ML290 (5 μM) shows anti-fibrotic, relaxin-like gene expression at 24 and 72 h in activated human hepatic stellate cells[1].

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