DBCO-PEG4-Maleimide


CAS No. : 1480516-75-3

1480516-75-3
Price and Availability of CAS No. : 1480516-75-3
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Cat. No. : HY-120770
M.Wt: 674.74
Formula: C36H42N4O9
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 1480516-75-3 :

DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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