Thiabendazole
CAS No. : 148-79-8
(Synonyms: Tiabendazole; 2-(4-Thiazolyl)benzimidazole)
| Size | Price | Stock |
|---|---|---|
| 500mg | $25 | In-stock |
| 1g | $35 | In-stock |
| 5g | $50 | In-stock |
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| Cat. No. : | HY-B0263 |
| M.Wt: | 201.25 |
| Formula: | C10H7N3S |
| Purity: | >98 % |
| Solubility: | H2O : < 0.1 mg/mL (ultrasonic);DMSO : 50 mg/mL (ultrasonic) |
Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling[1][2][3][4][5].
In Vitro: Thiabendazole (0/50/100/200/300/400/500 μM, 24/48/72 h) time- and dose-dependently inhibits B16F10 and B16 cells proliferation[2].
Thiabendazole (250 μM, 16 h) inhibits angiogenesis in Xenopus embryos and disrupts newly established vasculature[3].
In Vivo: Thiabendazole (50 mg/kg, 27 days) slows tumor growth in a mouse Xenopus model[3].
Thiabendazole (0/0.5/1/2/4/5/10/20/ mg/L, 0-96 hpf) induces developmental defects in zebrafish through apoptosis, oxidative stress, and changes of PI3K/Akt and MAPK pathwayssup>[4].
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