Ditiocarb sodium

Ditiocarb sodium (Sodium diethyldithiocarbamate) is an orally active copper reagent. Ditiocarb sodium exhibits activities such as antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. Ditiocarb sodium can be used in the research of tumors, inflammatory, and immune-related diseases^[1][2][3][4]. In Vitro: Ditiocarb sodium can act as an accelerator in the cementation of copper from copper sulfate solution on zinc. It reacts with Cu²⁺ solution to form a copper diethyldithiocarbamate complex, thereby increasing the rate of copper cementation. The higher its concentration, the more significant the increase in the cementation rate^[1]. In Vivo: Ditiocarb sodium (500-750 mg/kg; intraperitoneal injection; single dose) can inhibit Cisplatin (HY-17394)-induced nephrotoxicity and gastrointestinal toxicity in rats^[3].
Ditiocarb sodium (80-100 μmol; intraperitoneal injection; twice a week; 22 weeks) exhibits antitumor activity in a mouse skin tumor model^[4].