DCG-IV
CAS No. : 147782-19-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $730 | In-stock |
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| 10 mg | Get quote | |
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| Cat. No. : | HY-101335 |
| M.Wt: | 203.15 |
| Formula: | C7H9NO6 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 20 mg/mL |
DCG-IV is a potent agonist of group II mGluRs with EC50s of 0.35 and 0.09 μM for mGlu2R and mGlu3R, reapectively. DCG-IV is also a competitive antagonist at group I (IC50: mGlu1R/5R=389/630 μM) and III receptors (IC50: mGlu4R/6R/7R/8R= 22.5/39.6/40.1/32 μM). DCG-IV has anticonvulsive and neuroprotective effects[1][2]. In Vitro: DCG-IV is also an NMDA receptor agonist in the rat cortical slice[3]. In Vivo: DCG-IV (1-10 mg/kg; i.p.) depresses the phencyclidine (PCP)-induced hyperlocomotion[4].
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