(R)-(+)-Mequitazine
CAS No. : 147780-50-5
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| Cat. No. : | HY-124626 |
| M.Wt: | 322.47 |
| Formula: | C20H22N2S |
| Purity: | >98 % |
| Solubility: |
(R)-(+)-Mequitazine is a histamine H1 receptor antagonist that mainly undergoes bio-transformation via human liver microsomes, resulting in hydroxylated and S-oxidized metabolites. (R)-(+)-Mequitazine competitively binds to the H1 receptors in gastrointestinal, vascular, and respiratory effect cells, thus blocking the endogenous activity of histamine. (R)-(+)-Mequitazine has an inhibitory effect on CYP3A-catalyzed midazolam 1’-hydroxylase. (R)-(+)-Mequitazine can be used in the study of various allergic diseases[1][2].
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