DiMNF
CAS No. : 14756-24-2
(Synonyms: 3',4'-Dimethoxy-αNF)
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $350 | In-stock |
| 50mg | $550 | In-stock |
| 100mg | $950 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-103222 |
| M.Wt: | 332.35 |
| Formula: | C21H16O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 70°C) |
DiMNF (3',4'-Dimethoxy-αNF) is a selective aryl hydrocarbon receptor (AHR) modulator. DiMNF is a competitive AHR ligand (IC50 = 21 nM) with apparent antagonistic activity. DiMNF can be used as an anti-inflammatory agent[1].
In Vitro:DiMNF (3',4'-Dimethoxy-αNF) (10 μM; 4 h) minimally influences AHR gene battery[1].
DiMNF (10 μM; 1 h) effectively suppresses cytokine-mediated inflammatory gene expression[1].
DiMNF adopts a unique orientation within the ligand binding pocket of AHR[1].
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