Loviride


CAS No. : 147362-57-0

(Synonyms: R 89439)

147362-57-0
Price and Availability of CAS No. : 147362-57-0
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10mg $140 In-stock
25mg $300 In-stock
50mg $480 In-stock
100mg $765 In-stock
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Cat. No. : HY-15355
M.Wt: 351.23
Formula: C17H16Cl2N2O2
Purity: >98 %
Solubility: DMSO : 62.5 mg/mL (ultrasonic)
Introduction of 147362-57-0 :

Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 µM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells[1]. IC50 & Target: IC50: 0.3 µM (Reverse transcriptase)[1] In Vitro: Loviride (0.01 µM) inhibits HIV-1(IIIB) replication in MT-4 cells, also inhibits HIV-2 and SIV, with EC50s of 85.5, 7.4 µM for HIV-2 (ROD), HIV-2 (EHO), and 11.4, 28.5, 57.0 µM for SIV (mac251), SIV (agm3), SIV (mndGB1), respectively[1].

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