TT-232
CAS No. : 147159-51-1
(Synonyms: CAP-232; TLN-232)
| Size | Price | Stock |
|---|---|---|
| 1mg | $80 | In-stock |
| 5mg | $165 | In-stock |
| 10mg | $270 | In-stock |
| 25mg | $550 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-105172 |
| M.Wt: | 947.13 |
| Formula: | C45H58N10O9S2 |
| Purity: | >98 % |
| Solubility: | H2O : < 0.1 mg/mL (ultrasonic) |
TT-232 (CAP-232), a somatostatin derivative, is a peptide SSTR1/SSTR4 agonist. TT-232 inhibits cancer cell proliferation and induces apoptosis. TT-232 is also a broad-spectrum anti-inflammatory and analgesic agent[1][2][4].
In Vitro:TT-232 (10 μg/mL, 48 h) induces apoptosis in human colon (HT-29 and SW620), pancreatic (818), leukemia (K-562), melanoma (WM 938/B, M-1 and EP) and lymphoma (HT-58) tumor cell lines[1].
TT-232 (20-30 μg/mL, 24 h) shows antiproliferative effect on various human tumor cell lines[2].
In Vivo:TT-232 (15-750 μg/kg/day, twice a day) inhibits tumor growth in mice transplanted with Colon 26 cell[2].
TT-232 (0.6 or 15 μg/kg s.c or i.p.) shows antitumor effect on P-388 rodent lymphocytic leukemia tumor mice[3].
TT-232 (7.5-20 μg/kg, i.v.) inhibits Carrageenin-induced paw oedema in rats[4].
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