L-Proline


CAS No. : 147-85-3

147-85-3
Price and Availability of CAS No. : 147-85-3
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25g $12 In-stock
100g $18 In-stock
500g $27 In-stock
1000g $53 In-stock
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Cat. No. : HY-Y0252
M.Wt: 115.13
Formula: C5H9NO2
Purity: >98 %
Solubility: H2O : 50 mg/mL (ultrasonic);DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 147-85-3 :

L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. In Vitro:L-Proline (1 g/L, 48 h) inhibits AFB1- or AFM1-induced apoptosis through downregulation of PRODH expression and its downstream apoptotic factors (Bax, Bcl-2 and cleaved Caspase-3)[1].
L-Proline (40-400 μM, 4 days) activates the mTOR signaling pathway, induces the differentiation of mouse embryonic stem cells (ES cells)[2].
In Vivo:L-Proline (10 g/kg, po for 28 days) exhibits protective effect against renal oxidative damage and dysfunction caused by AFB1 and AFM1[1].

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