mPGES1-IN-3


CAS No. : 1469976-70-2

1469976-70-2
Price and Availability of CAS No. : 1469976-70-2
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Cat. No. : HY-100864
M.Wt: 538.85
Formula: C24H16ClF5N4O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1469976-70-2 :

mPGES1-IN-3 (Compound 17d) is a potent and selective microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor, which exhibits excellent mPGES-1 enzyme (IC50: 8 nM), cell (A549 IC50: 16.24 nM) and human whole blood potency (IC50: 249.9 nM)[1]. IC50 & Target: IC50: 8 nM (mPGES-1)[1]

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