LGB321 (monohydrochloride)
CAS No. : 1469925-36-7
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| Cat. No. : | HY-15901A |
| M.Wt: | 493.91 |
| Formula: | C23H23ClF3N5O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
LGB321 monohydrochloride is a potent, selective, orally active and ATP competitive inhibitor of all three PIM kinases. LGB321 monohydrochloride inhibits proliferation, mTOR-C1 signaling and phosphorylation of BAD in a number of cell lines derived from diverse hematologic malignancies. LGB321 monohydrochloride can be used for the research of hematologic malignancies[1].
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