Ziprasidone
CAS No. : 146939-27-7
(Synonyms: CP-88059)
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $79 | In-stock |
| 25mg | $132 | In-stock |
| 50mg | $198 | In-stock |
| 100mg | $255 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-14542 |
| M.Wt: | 412.94 |
| Formula: | C21H21ClN4OS |
| Purity: | >98 % |
| Solubility: | DMSO : 13.33 mg/mL (ultrasonic;warming;heat to 60°C) |
Ziprasidone (CP-88059), an orally active antipsychotic agent, is a combined 5-HT and dopamine receptor antagonist[1]. Ziprasidone mesylate trihydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM)[1]. In Vitro: Ziprasidone (0-500 nM, 150 seconds) blocks wild-type hERG current[2]. In Vivo: Ziprasidone (oral gavage; 20 mg/kg; once daily; 7 weeks) results in weight loss, low level physical activity, high resting energy expenditure and greater capacity for thermogenesis when subjected to cold[3].
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