6H05
CAS No. : 1469338-01-9
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| Cat. No. : | HY-12408 |
| M.Wt: | 476.12 |
| Formula: | C20H30ClN3O2S3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). IC50 value: Target: K-Ras G12C 6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2].
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