Dantrolene (sodium) (Standard)
CAS No. : 14663-23-1
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| Cat. No. : | HY-14657R |
| M.Wt: | 336.23 |
| Formula: | C14H9N4NaO5 |
| Purity: | >98 % |
| Solubility: |
Dantrolene (sodium) (Standard) is the analytical standard of Dantrolene (sodium). This product is intended for research and analytical applications. Dantrolene sodium is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 μM and an IC50 of 52.3 μM. Dantrolene sodium is also a calcium channel protein inhibitor. Dantrolene sodium inhibits the release of Ca2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene sodium offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties[1][2][3][4][5][6][7][8][9][10][11].
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