Spindlactone B


CAS No. : 1465248-60-5

(Synonyms: SPL-B)

1465248-60-5
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Cat. No. : HY-112500
M.Wt: 454.48
Formula: C27H22N2O5
Purity: >98 %
Solubility:
Introduction of 1465248-60-5 :

Spindlactone B is a TACC3 inhibitor. Spindlactone B reduces the level of acetylated Microtubules. Spindlactone B can be used in the research of neurological diseases[1]. In Vitro:Spindlactone B (0.25 µg/mL; 48 h) reduces somatic microtubule acetylation, neurite growth, and axon formation in primary mouse cortical neurons, while Cep120 overexpression partially reverses these effects[1].

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