CDD0102
CAS No. : 146422-58-4
(Synonyms: CDD0102A)
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| Cat. No. : | HY-U00230 |
| M.Wt: | 180.21 |
| Formula: | C8H12N4O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
CDD0102 is a potent M1 Muscarinic receptor agonist. IC50 & Target: mAChR[1] In Vitro: CDD0102 (CDD-0102) is an efficacious muscarinic agonist in cell lines expressing M1 receptors. CDD0102 displays much lower activity at M3 and M5 receptors[1]. In Vivo: After i.p. injections, CDD0102 (CDD-0102) crosses the blood-brain barrier (BBB) in a dose-dependent manner. In toxicological studies, the LD50 of CDD0102 is 190 mg/kg following i.p. injections and greater than 1,000 mg/kg following oral administration. In follow-up studies, after oral administration at a dose of 10 mg/kg, CDD0102 fully reverses memory deficits associated with IgG-192 saporin administration. Again, no side effects are observed at this dose[1].
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