Selenomethionine


CAS No. : 1464-42-2

(Synonyms: Seleno-DL-methionine; DL-Selenomethionine)

1464-42-2
Price and Availability of CAS No. : 1464-42-2
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100mg $32 In-stock
250mg $79 In-stock
1g $256 In-stock
5g $911 In-stock
25g $1120 Get quote
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Cat. No. : HY-B1000
M.Wt: 196.11
Formula: C5H11NO2Se
Purity: >98 %
Solubility: H2O : 12.5 mg/mL (ultrasonic)
Introduction of 1464-42-2 :

Selenomethionine is a naturally occurring amino acid containing selenium that has oral activity and is a common natural food source. Selenomethionine has antitumor activity[1][2][3]. In Vitro:Selenomethionine (50 μM, 12 h) decreases the hatchability and glutathione consumption of Japanese rice embryos, but does not affect selenium accumulation[1].
Selenomethionine (45-135 μM, 24 h) inhibits the growth of MCF-7/S breast cancer, DU-145 prostate cancer cells and UAC-375 melanoma cells in a dose-dependent manner[2].
Selenomethionine (25-500 μM, 24 h) inhibits TBHP-induced oxidative stress and mitochondrial division by activating the Nrf2 pathway, thereby inhibiting the apoptosis of nucleus pulposus cells (NPCs) and improving intervertebral disc degeneration (IDD)[3].
In Vivo:Selenomethionine (2 mg/kg/day, gavage for 4 weeks) can improve the degenerative performance in the acupuncturally-induced rat IDD model[3].

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