BM212
CAS No. : 146204-42-4
| Size | Price | Stock |
|---|---|---|
| 1mg | $54 | In-stock |
| 5mg | $135 | In-stock |
| 10mg | $216 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-100725 |
| M.Wt: | 414.37 |
| Formula: | C23H25Cl2N3 |
| Purity: | >98 % |
| Solubility: | Ethanol : 5.56 mg/mL (ultrasonic);DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C) |
BM212 is a potent Mycobacterial membrane protein Large 3 (MmpL3) inhibitor. BM212 has strong bactericidal activity against both M. tuberculosis and some nontuberculosis mycobacteria. BM212 exhibits antimycobacterial activity against M. tuberculosis H37Rv with an MIC of 5 µM[1][2].
IC50 & Target:M. tuberculosis[1]
In Vitro:BM212 (2 μg/mL and 8 μg/mL) leads to major structural changes in the cell of M. abscessus CIP104536T S and R variants and results in the complete loss of the hydrophobic nanodomains observed on S cells but no significantly affect on R cells at dose of 2 μg/mL[3].
BM212 (0.5-10 μg/mL, 7 days) inhibits the activity of Mycobacterium avium in U937 cells in a dose-dependent manner with a MIC of 0.5 μg/mL and 100% inhibition starting at a concentration of 1 μg/mL[4].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- BM212
- Cat. No.:
- HY-100725
- Quantity:
Your information is safe with us.