Ketopioglitazone
CAS No. : 146062-45-5
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| Cat. No. : | HY-119311 |
| M.Wt: | 370.42 |
| Formula: | C19H18N2O4S |
| Purity: | >98 % |
| Solubility: |
Pioglitazone ketone is an active metabolite of the PPARγ agonist Pioglitazone (HY-13956). Formation of pioglitazone ketone occurs primarly through cytochrome P450 (CYP) isoform CYP2C8-mediated metabolism of pioglitazone. Pioglitazone ketone (100 mg/kg in the diet) reduces blood glucose levels in a KKAy mouse model of type 2 diabetes.
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