SC 51089
CAS No. : 146033-02-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $500 | Get quote |
| 10mg | $750 | Get quote |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-108563 |
| M.Wt: | 459.33 |
| Formula: | C22H20Cl2N4O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C) |
SC 51089 is a selective antagonist of prostaglandin E2 EP1 receptor, with Kis of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively. SC 51089 exhibits neuroprotective activity[1][2][3]. In Vitro:SC 51089 (5 μM; 24 h) attenuates prostaglandin E2 (PGE2)-induced the death of neuronal cells exposed to t-BuOOH[2]. In Vivo:SC 51089 (40 μg/kg; infused i.p. for 28 d) ameliorates motor coordination and balance dysfunction and rescues long-term memory deficit in R6/1 mouse model of HD[3].
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