GJ103
CAS No. : 1459687-89-8
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| Cat. No. : | HY-101203 |
| M.Wt: | 342.37 |
| Formula: | C16H14N4O3S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
GJ103 is a read-through compound that can induce read through of premature stop codons. GJ103 has potential for the research of genetic disorders caused by nonsense mutations[1].
In Vivo:GJ103 (10-30 μM; 4 days) induces ATM kinase activity in AT153LA cells with a homozygous TGA mutation and a homozygous TAA mutation[1].
GJ103 does not show obvious cytotoxicity in A-T cells at concentration as high as 300 µM[1].
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