CGP-53353
CAS No. : 145915-60-2
(Synonyms: DAPH-7)
| Size | Price | Stock |
|---|---|---|
| 5mg | $160 | In-stock |
| 10mg | $250 | In-stock |
| 25mg | $550 | In-stock |
| 50mg | $950 | In-stock |
| 100mg | $1550 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-108600 |
| M.Wt: | 365.33 |
| Formula: | C20H13F2N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL |
CGP-53353 (DAPH-7) is an potent PKC inhibitor with IC50s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. CGP-53353 can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells. CGP-53353 can be used for researching atherosclerosis of diabetic patients[1]. In Vitro:CGP-53353 (DAPH-7) (1 μM; 48-96 hours) inhibits glucose-induced cell proliferation in A10 cells[1]. CGP-53353 (1 μM ; 0-48 hours) inhibits the glucose-induced increase and acceleration of DNA synthesis in A10, also blocks the glucose-induced increase of S-phase cell percentage[1].
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