(-)-BO 2367
CAS No. : 145902-81-4
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| Cat. No. : | HY-117657 |
| M.Wt: | 437.87 |
| Formula: | C21H22ClF2N3O3 |
| Purity: | >98 % |
| Solubility: |
(-)-BO 2367, an antimicrobial quinolone, is a strong mammalian and bacterial topoisomerase II inhibitor. (-)-BO 2367 shows IC50 values with 3.8 μM, 0.5 μM, and 1 μM against the DNA relaxation activity of L1210 topoisomerase II and the supercoiling activities of Escherichia coli gyrase and Micrococcus luteus gyrase, respectively. (-)-BO 2367 is a potent antitumor agent[1].
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