| Size | Price | Stock |
|---|---|---|
| 5mg | $84 | In-stock |
| 10mg | $132 | In-stock |
| 50mg | $396 | In-stock |
| 100mg | $640 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-13673A |
| M.Wt: | 1000.00 |
| Formula: | C59H84N18O14·xC2H4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 28 mg/mL;H2O : 100 mg/mL (ultrasonic) |
Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer[1][2].
IC50 & Target:GnRH[1]
In Vitro: Goserelin (1 nM-1 mM; 48-72 hours) promotes EOC cell apoptosis[1].
Goserelin (100 μM; 24-72 hours) regulates the expression of human apoptosis-related genes in SKOV3-ip cells[1].
Goserelin (100 μM; 24-72 hours) promotes EOC cell apoptosis by upregulating FOXO1 through the PI3K/AKT signaling pathway[1].
In Vivo: Goserelin (100 μg; s.c.; daily; for 19 days) significantly increases the proportion of apoptotic cells in the subcutaneous xenograft tumors[1].
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