Tasosartan
CAS No. : 145733-36-4
(Synonyms: WAY-ANA 756)
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| 10mg | $240 | In-stock |
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| Cat. No. : | HY-A0250 |
| M.Wt: | 411.46 |
| Formula: | C23H21N7O |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Tasosartan is a long-acting angiotensin II (AngII) receptor antagonist. IC50 & Target: Angiotensin II (AngII) receptor[1] In Vitro: Tasosartan is an orally active nonpeptide AngII antagonist that has demonstrates specific and selective AT1 receptor antagonistic activity in vitro. IC50 for inhibition of specific binding of 125I-AngII to rat adrenal membrane in the absence of proteins in binding buffer is 1.2±0.6 nM[1]. In Vivo: Administration of Tasosartan at doses of 1.0 and 3.0 mg/kg (iv) significantly (p<0.05) attenuates the pressor response to angiotensin-II in rats[2].
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