PL553


CAS No. : 1456872-74-4

1456872-74-4
Price and Availability of CAS No. : 1456872-74-4
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5mg $215 In-stock
10mg $360 In-stock
25mg $720 In-stock
50mg $1200 In-stock
100mg $2000 In-stock
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Cat. No. : HY-U00452
M.Wt: 508.49
Formula: C28H23F3N2O4
Purity: >98 %
Solubility: DMSO : 200 mg/mL (ultrasonic)
Introduction of 1456872-74-4 :

PL553 is a specific and high-affinity fluorigenic substrate of Leukotriene A4 hydrolase, with a λmax of 210 nm and λem of 410 nm. In Vitro:PL553 is a specific and high-affinity fluorigenic substrate of Leukotriene A4 hydrolase (LTA4H), with a maximum absorption (λmax) of 210 nm and maximum emission (λem) of 410 nm. PL553 is a better LTA4H substrate than (l)-Ala-β-naphthylamide, and resistant to cleavage by other aminopeptidases, but can be cleaved by FAAH. PL553 (40 μM) is used to evaluate the potencies of known inhibitors toward LTA4H[1].

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