AD 0261
CAS No. : 145600-69-7
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| Cat. No. : | HY-U00005 |
| M.Wt: | 451.55 |
| Formula: | C27H31F2N3O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
AD 0261 is a radical scavenger which displays strong inhibitory action on the generation of lipid peroxides and superoxide anions. In Vitro: AD 0261 displays strong inhibitory action on the generation of lipid peroxides (IC50=0.022 μM) and superoxide anions (IC50= 0.9-4.0 μM). AD 0261 inhibits cytokine release and/or production from PHA-P-stimulated lymphocytes in a dose-dependent manner. AD 0261 inhibits all parameters which are indicative of lymphocyte activation with 50% inhibition being achieved in a range of 1-10 μM. AD 0261 suppresses ornithine decarboxylase activity, the IC50 value being around 1.0 μM[1].
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