Bupranolol
CAS No. : 14556-46-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $105 | In-stock |
| 10mg | $165 | In-stock |
| 25mg | $320 | In-stock |
| 50mg | $480 | In-stock |
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| Cat. No. : | HY-A0252 |
| M.Wt: | 271.78 |
| Formula: | C14H22ClNO2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
Bupranolol is an orally active, competitive and non-selective β-adrenoceptor antagonist without intrinsic sympathomimetic activity[1]. IC50 & Target: β-adrenoceptor[1] In Vitro: Bupranolol (1~3 μM) shifts isoprenaline-induced relaxation in the presence of 30 μM propranolol. Bupranolol acts as a competitive antagonist of isoprenaline-induced relaxation in the presence of 300 nM propranolol, with a pA2 value of 5.90. Bupranolol antagonizes β1- and β2-ARs with pA2 values of ≈9.0, and also antagonizes β3-AR with a pA2 value of 6.0[1].
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